HCV(CMIA)

Ọrịa ịba ọcha n'anya C ka amabeghị.Mgbe HCV na-emegharị na mkpụrụ ndụ imeju, ọ na-ebute mgbanwe na nhazi na ọrụ nke mkpụrụ ndụ imeju ma ọ bụ na-egbochi njikọ nke protein cell imeju, nke nwere ike ime ka mmebi na necrosis nke mkpụrụ ndụ imeju, na-egosi na HCV na-emebi imeju ozugbo ma na-ekere òkè na pathogenesis.Otú ọ dị, ọtụtụ ndị ọkachamara mgbakọ na mwepụ kwenyere na mmeghachi omume immunopathological cell nwere ike ịrụ ọrụ dị mkpa.Ha chọpụtara na ịba ọcha n'anya C, dị ka ịba ọcha n'anya B, nwere ọkachasị CD3+ na-abanye n'ime anụ ahụ ya.Cytotoxic T mkpụrụ ndụ (TC) na-awakpo kpọmkwem mkpụrụ ndụ ebu n'obi nke ọrịa HCV, nke nwere ike imebi cell imeju.


Nkọwa ngwaahịa

Mkpado ngwaahịa

Ozi bụ isi

Aha ngwaahịa Katalọgụ Ụdị Onye ọbịa/Isi iyi Ojiji Ngwa Epitope COA
HCV Core-NS3-NS5 fusion antigen BMIHCV203 Antigen E.coli Were CMIA,
WB
/ Budata
HCV Core-NS3-NS5 fusion antigen BMIHCV204 Antigen E.coli Conjugate CMIA,
WB
/ Budata
HCV Core-NS3-NS5 ngwakọta antigen-Bio BMIHCVB02 Antigen E.coli Conjugate CMIA,
WB
/ Budata
HCV Core-NS3-NS5 fusion antigen BMIHCV213 Antigen Ụlọ elu HEK293 Conjugate CMIA,
WB
/ Budata

Ọrịa ịba ọcha n'anya C ka amabeghị.Mgbe HCV na-emegharị na mkpụrụ ndụ imeju, ọ na-ebute mgbanwe na nhazi na ọrụ nke mkpụrụ ndụ imeju ma ọ bụ na-egbochi njikọ nke protein cell imeju, nke nwere ike ime ka mmebi na necrosis nke mkpụrụ ndụ imeju, na-egosi na HCV na-emebi imeju ozugbo ma na-ekere òkè na pathogenesis.Otú ọ dị, ọtụtụ ndị ọkachamara mgbakọ na mwepụ kwenyere na mmeghachi omume immunopathological cell nwere ike ịrụ ọrụ dị mkpa.Ha chọpụtara na ịba ọcha n'anya C, dị ka ịba ọcha n'anya B, nwere ọkachasị CD3+ na-abanye n'ime anụ ahụ ya.Cytotoxic T mkpụrụ ndụ (TC) na-awakpo kpọmkwem mkpụrụ ndụ ebu n'obi nke ọrịa HCV, nke nwere ike imebi cell imeju.

RIA ma ọ bụ ELISA

A na-eji Radioimmunodiagnosis (RIA) ma ọ bụ immunosorbent assay (ELISA) jikọtara enzyme iji chọpụta mgbochi HCV na serum.Na 1989, Kuo et al.guzobere usoro redioimmunoassay (RIA) maka mgbochi C-100.Ka oge na-aga, ụlọ ọrụ Ortho rụpụtara nke ọma immunosorbent assay (ELISA) jikọtara enzyme iji chọpụta mgbochi C-100.Ụzọ abụọ a na-eji yist recombinant egosipụtara nje antigen (C-100-3, protein nke NS4 nwere koodu 363, nke nwere amino acid 363), mgbe emechara ya ọcha, a na-ekpuchi ya na obere oghere efere plastik, wee tinye ya na serum a nwalere.A na-ejikọta antigen nje na mgbochi C-100 n'ime ọbara a nwalere.N'ikpeazụ, a na-agbakwunye isotope ma ọ bụ enzyme akpọrọ mouse anti human lgG monoclonal antibody, na-agbakwunyere mkpụrụ osisi maka ikpebi agba.


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