NKỌWA NA NKWAWA NWA Nnwale
Helicobacter pylori jikọtara ya na ọrịa dị iche iche nke eriri afọ gụnyere dyspepsia na-abụghị ọnya, ọnya duodenal na ọnya afọ na arụ ọrụ, gastritis na-adịghị ala ala.Ọgbasa nke ọrịa H. pylori nwere ike gafere 90% na ndị ọrịa nwere akara na akara nke ọrịa eriri afọ.Nnyocha e mere n'oge na-adịbeghị anya na-egosi njikọ nke ọrịa H. pylori na ọrịa kansa afọ.
Enwere ike ibunye pylori site na iri nri ma ọ bụ mmiri nke ihe fecal metọọrọ.Achọpụtara ọgwụ nje na ngwakọta bismuth ka ọ dị irè n'ịgwọ ọrịa H. Pylori na-arụ ọrụ..H.A na-ahụta ọrịa pylori ugbu a site na ụzọ nnwale mkpasu iwe dabere na endoscopy na biopsy (ya bụ histology, omenala) ma ọ bụ ụzọ nnwale na-adịghị emerụ ahụ dị ka urea breath test (UBT), serologic antibody test na stool antigen test.UBT chọrọ akụrụngwa ụlọ nyocha dị oke ọnụ yana oriri nke reagent redioaktivu.Nnwale serologic antibody adịghị ama ọdịiche dị n'etiti ọrịa na-arụ ọrụ ugbu a yana mkpughe gara aga ma ọ bụ ọrịa a gwọọla.Nnwale antigen stool na-achọpụta antigen dị na nsị, nke na-egosi ọrịa H. pylori na-arụ ọrụ.Enwere ike iji ya nyochaa ịdị irè ọgwụgwọ yana nlọghachi nke ọrịa. H. pylori Ag Rapid Test na-eji colloidal gold conjugated monoclonal anti-H.pylori antibody na ọzọ monoclonal mgbochi H.pylori mgbochi iji chọpụta kpọmkwem H. pylori antigen dị n'ụdị fecal nke onye ọrịa butere ya.Nnwale a bụ enyi na enyi, nke ziri ezi, yana nsonaazụ ya dị n'ime nkeji iri na ise.
Ụkpụrụ
Nnwale H. pylori Ag Rapid bụ immunoassay chromatographic mpụta Sanwichi.Mpempe ule ahụ nwere: 1) pad conjugate nwere agba burgundy nwere mgbochi H monoclonal.pylori antibody jikọtara ya na colloidal gold (anti-Hp conjugates) na 2) nitrocellulose membrane strip nwere eriri ule (T line) na akara njikwa (C ahịrị).Ejikwa mgbochi H monoclonal ọzọ kpuchie T ahịrị.pylori antibody, na ahịrị C ejiri ọgwụ mgbochi ewu IgG kpuchie ya.
Mgbe a na-ekesa oke nha nha nke fecal ewepụtara n'ime olulu mmiri nlele nke cassette a, ihe nlere ahụ na-akwaga site na capillary omume gafee cassette ahụ.H. pylori antigens, ọ bụrụ na ọ dị na ihe nlere ahụ, ga-ejikọta na mgbochi Hp conjugates. Mgbe ahụ, a na-ejide immunocomplex na akpụkpọ ahụ site na mgbochi nke kpuchiri mbụ nke na-emepụta akara T nke burgundy, nke na-egosi nsonaazụ H. pylori dị mma.Enweghị akara T na-egosi na ntinye nke antigens H. pylori dị na ihe nlele ahụ dị n'okpuru ọkwa a na-achọpụta, na-egosi nsonaazụ H. pylori na-adịghị mma. Nnwale ahụ nwere njikwa ime (C line) nke kwesịrị igosi akara agba agba burgundy. na immunocomplex nke ewu mgbochi òké IgG / òké IgG-gold conjugate n'agbanyeghị nke agba mmepe na T ahịrị.Ọ bụrụ na ahịrị C etoliteghị, nsonaazụ ule abaghị uru yana a ga-eji ngwaọrụ ọzọ nwaleghachi ihe nlele ahụ.
